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Research Associate/Senior Research Associate - Organic/Antibody Drug Conjugation (ADC)

o2h Group · Ahmedabad, Gujarāt, India

Data Science / AI / Machine LearningSenior LevelQuick applyfull-time4 days ago

About The Role

Principal Scientist

  • Lead and manage a multidisciplinary scientific team of 12-15 FTEs ensuring high-quality project delivery.
  • Handle client communications and independently manage technical calls with global stakeholders.
  • Oversee project planning, execution, timelines, and resource allocation.
  • Provide scientific guidance, troubleshooting, and mentoring to team members.
  • Ensure compliance with quality, safety, and organizational standards.
  • Collaborate cross-functionally to support business and operational goals.

Organic Chemist

  • Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance
  • Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography
  • Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations
  • Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately

Peptide Chemist

  • Hands-on expertise in solid-phase and solution-phase peptide synthesis using automated synthesisers like Syro and Liberty CEM
  • Strong experience in peptide purification, characterisation, and analytical techniques, including HPLC, LCMS, and MS
  • Capable of independently handling medium- to large-scale peptide synthesis (1 g to 1 kg scale) with troubleshooting abilities
  • Skilled in laboratory operations, equipment maintenance, SHE compliance, literature review, and accurate experimental documentation

Scaleup Chemist

  • Experience in process R&D, scale-up synthesis, and purification from gm to kg scale
  • Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities
  • Proficient in 1H NMR, HPLC, and LCMS interpretation
  • Strong project execution and team collaboration skills

Antibody Drug Conjugation Chemist (ADC)

  • Synthesis and purification of complex antibody drug conjugate (ADC) molecules
  • Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs
  • Synthesis of highly potent drug molecules – payloads
  • Purification of complex and large molecules by flash column and HPLC
  • Handling various type chemistry with different payloads
  • Interpretation and characterisation of higher molecular weight compounds

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