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Research Associate/Senior Research Associate - Organic/Antibody Drug Conjugation (ADC)
o2h Group · Ahmedabad, Gujarāt, India
About The Role
Principal Scientist
- Lead and manage a multidisciplinary scientific team of 12-15 FTEs ensuring high-quality project delivery.
- Handle client communications and independently manage technical calls with global stakeholders.
- Oversee project planning, execution, timelines, and resource allocation.
- Provide scientific guidance, troubleshooting, and mentoring to team members.
- Ensure compliance with quality, safety, and organizational standards.
- Collaborate cross-functionally to support business and operational goals.
Organic Chemist
- Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance
- Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography
- Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations
- Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately
Peptide Chemist
- Hands-on expertise in solid-phase and solution-phase peptide synthesis using automated synthesisers like Syro and Liberty CEM
- Strong experience in peptide purification, characterisation, and analytical techniques, including HPLC, LCMS, and MS
- Capable of independently handling medium- to large-scale peptide synthesis (1 g to 1 kg scale) with troubleshooting abilities
- Skilled in laboratory operations, equipment maintenance, SHE compliance, literature review, and accurate experimental documentation
Scaleup Chemist
- Experience in process R&D, scale-up synthesis, and purification from gm to kg scale
- Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities
- Proficient in 1H NMR, HPLC, and LCMS interpretation
- Strong project execution and team collaboration skills
Antibody Drug Conjugation Chemist (ADC)
- Synthesis and purification of complex antibody drug conjugate (ADC) molecules
- Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs
- Synthesis of highly potent drug molecules – payloads
- Purification of complex and large molecules by flash column and HPLC
- Handling various type chemistry with different payloads
- Interpretation and characterisation of higher molecular weight compounds
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