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Research Associate, Molecular & Cellular Immunology

Stylus Medicine · Cambridge, MA, United States

Data Science / AI / Machine LearningImported listingfull-timeabout 4 hours ago

About The Role

<div class="content-intro"><p><strong>About Stylus Medicine: </strong></p>
<p><span class="il">Stylus</span> Medicine is developing transformative <em>in vivo</em> genetic medicines to unlock cures. <span class="il">Stylus</span> combines engineered recombinases with non-viral delivery to specifically encode therapeutics. The company’s approach is versatile and modular, with potential therapeutic application across oncology, autoimmune, genetic diseases, and beyond.</p></div><p><strong>About the Role:</strong></p>
<p>Stylus Medicine is seeking a highly motivated and collaborative Research Associate<strong> </strong>to join the Molecular and Cellular Immunology team. In this role, the Research Associate will assist in generating nucleic acid materials and performing <em>in vitro</em> cell experiments, supporting the advancement of genetic medicines that leverage engineered recombinases delivered through non-viral methods. Working closely with cross-functional teams, this is a unique opportunity to work on the front lines of innovation and contribute to the advancement of transformational therapies.</p>
<p><strong>Key Responsibilities & Accountabilities:</strong></p>
<ul>
<li>Perform <em>in vitro</em> T cell experiments to evaluate efficiency of recombinase-based engineering strategies and characterize the functional ability of resulting CAR-T cells</li>
<li>Perform cloning and prepare nucleic acid and/or LNPs to support cell culture experiments</li>
<li>Analyze and interpret data and produce data reports to inform project direction</li>
<li>Effectively communicate findings to internal teams</li>
<li>Maintain detailed and accurate laboratory records in compliance with data integrity and documentation standards</li>
</ul>
<p><strong>Qualifications & Skills:</strong></p>
<ul>
<li>Bachelor’s degree in Biology, Bioengineering, Immunology, or a related field</li>
<li>Hands-on molecular biology experience, including PCR, cloning, bacterial transformations, minipreps, maxipreps, and <em>in vitro</em> transcription</li>
<li>Hands-on mammalian cell culture expertise, including culturing tumor cell lines and primary T cells/PBMCs, co-culture experiments, flow cytometry, and genomic DNA extraction</li>
<li>Familiarity producing targeted LNPs and/or working with CAR-T cells is preferred</li>
<li>Demonstrated ability to execute, interpret, and troubleshoot experiments, both independently and collaboratively</li>
<li>Experience maintaining meticulous records, including documenting and maintaining an organized lab notebook, lab inventory, and experimental results</li>
<li>Excellent communication skills, with a team-first mindset and the ability to convey technical information</li>
<li>Highly collaborative working style and ability to adapt in a fast paced, rapidly developing environment</li>
<li>Enthusiasm and curiosity to learn and apply new lab techniques across a variety of sub-disciplines</li>
</ul>
<p>Pay Range: $85,000-$95,000</p>

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