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Assoc Director Safety Science

Erasca · Remote, Oregon, United States

Healthcare AdministrationRemoteImported listingfull-timeabout 1 hour ago

About The Role

<div class="content-intro"><p><span class="TextRun SCXW12482860 BCX8" lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW12482860 BCX8">Erasca is a clinical-stage precision oncology company focused on discovering, developing and commercializing medicines for the benefit of patients with cancer. Our programs take novel approaches to shutting down one of cancer’s </span><span class="NormalTextRun SCXW12482860 BCX8">most commonly mutated</span><span class="NormalTextRun SCXW12482860 BCX8"> signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “Erasca” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer.</span></span></p></div><p><strong>Associate Director Safety Science</strong></p>
<p><strong><span data-contrast="none">Position Summary:</span></strong><span data-contrast="none"> </span><span data-ccp-props="{"201341983":0,"335559739":0,"335559740":259}"> </span></p>
<p><span data-contrast="auto"><span data-ccp-parastyle="Normal (Web)">Reporting to the </span><span data-ccp-parastyle="Normal (Web)">Director</span><span data-ccp-parastyle="Normal (Web)">,</span><span data-ccp-parastyle="Normal (Web)"> Safety </span><span data-ccp-parastyle="Normal (Web)">Science</span><span data-ccp-parastyle="Normal (Web)">, the </span><span data-ccp-parastyle="Normal (Web)">Associate </span><span data-ccp-parastyle="Normal (Web)">Director</span><span data-ccp-parastyle="Normal (Web)">,</span><span data-ccp-parastyle="Normal (Web)"> Safety </span><span data-ccp-parastyle="Normal (Web)">Science </span><span data-ccp-parastyle="Normal (Web)">will provide safety science and pharmacovigilance support to molecules across the </span><span data-ccp-parastyle="Normal (Web)">Erasca</span><span data-ccp-parastyle="Normal (Web)"> portfolio. </span><span data-ccp-parastyle="Normal (Web)">The position will </span><span data-ccp-parastyle="Normal (Web)">support</span> <span data-ccp-parastyle="Normal (Web)">early and late phase development activities as a member of the safety team, providing essential safety oversight and input into all aspects of study management across the entire development portfolio. They will bring safety </span><span data-ccp-parastyle="Normal (Web)">expertise</span><span data-ccp-parastyle="Normal (Web)"> to interactions with internal stakeholders</span><span data-ccp-parastyle="Normal (Web)"> and</span> <span data-ccp-parastyle="Normal (Web)">r</span><span data-ccp-parastyle="Normal (Web)">egulatory </span><span data-ccp-parastyle="Normal (Web)">a</span><span data-ccp-parastyle="Normal (Web)">uthorities </span><span data-ccp-parastyle="Normal (Web)">and</span><span data-ccp-parastyle="Normal (Web)"> must have the ability to interact effectively in a multifunctional and multicultural team setting.</span><span data-ccp-parastyle="Normal (Web)"> Additionally, the </span><span data-ccp-parastyle="Normal (Web)">Associate </span><span data-ccp-parastyle="Normal (Web)">Director</span><span data-ccp-parastyle="Normal (Web)">,</span><span data-ccp-parastyle="Normal (Web)"> Safety Science will work closely with Safety Operations</span><span data-ccp-parastyle="Normal (Web)"> for </span><span data-ccp-parastyle="Normal (Web)">case review, medical review</span><span data-ccp-parastyle="Normal (Web)">,</span><span data-ccp-parastyle="Normal (Web)"> and study oversight for patient safety.  </span></span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335557856":16777215,"335559738":0,"335559739":0,"335559740":259}"> </span></p>
<p><span data-contrast="auto"><span data-ccp-parastyle="Normal (Web)">Note this position can be hybrid in our San Diego or South San Francisco locations or fully remote anywhere in the United States.</span></span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335557856":16777215,"335559738":0,"335559739":0,"335559740":259}"> </span></p>
<p><strong><span data-contrast="auto"><span data-ccp-parastyle="Normal (Web)">Essential Duties and </span><span data-ccp-parastyle="Normal (Web)">Responsibilities: </span></span></strong><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335557856":16777215,"335559738":0,"335559739":0,"335559740":259}"> </span></p>
<ul>
<li>Develop and maintain an understanding of the safety profile of assigned product(s) as well as understanding of the relevant strategic context (e.g., disease under study, safety profile of competitors, mechanism of action) </li>
<li>Responsible for assisting/overseeing signal detection and management activities including, but not limited to, ISMP maintenance.</li>
<li>Responsible for the preparation and maintenance of safety sections of the ISMP, DSUR, IND Annual reports and/or Reference Safety Information in the IB. </li>
<li>Present important safety issues to program teams for internal and external review. </li>
<li>Serve as safety science representative for clinical trial team meetings or investigator/site meetings</li>
<li>Contribute to the drafting of safety assessments and drug safety reports for individual cases or aggregate data for signals or in response to Regulatory Authority requests. </li>
<li>Review clinical protocols, study reports, Investigator's Brochure (IB), informed consent form (ICF) and other related documents to ensure alignment with the safety strategy and ensure the appropriateness of risk management strategies and risk communication. </li>
<li>May support non-molecule projects, due diligence evaluations, and other projects as needed. </li>
<li>Responsible for coordination and collaboration with vendors servicing Safety Science. </li>
<li>Accountable for the safety components of study reports, publications, aggregate reports, and high-level regulatory documents. </li>
<li>Perform all duties in keeping with the Company’s core values, policies, and all applicable regulations.</li>
</ul>
<p><strong><span data-contrast="auto"><span data-ccp-parastyle="Normal (Web)">Education and Experience</span></span></strong><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335557856":16777215,"335559738":0,"335559739":0,"335559740":259}"> </span></p>
<ul>
<li>Healthcare professional degree (MD, PharmD, or RN) required</li>
<li>4 or more years of drug development experience in the pharmaceutical or related industry including at least 2 years in drug safety </li>
<li>Broad understanding of the scientific aspects of safety, PV (including GVP, GCP), and clinical/patient risk management is essential ​</li>
<li>Demonstrated ability to lead and influence, with and without authority, in a fast paced environment</li>
<li>Exposure to Safety Operations and experience with data entry and administration of drug safety databases, such as Oracle Argus</li>
<li>Strong presentation skills, effective at summarizing and presenting the key considerations and decision points </li>
<li>Proven ability to effectively train others on departmental practices and processes</li>
<li>Strong learning orientation, curiosity, and commitment to science and patients</li>
</ul>
<p> </p>
<p><span data-contrast="auto"><span data-ccp-charstyle="wbzude"><span class="TextRun SCXW198344204 BCX8" lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW198344204 BCX8">The</span> <span class="NormalTextRun SCXW198344204 BCX8">anticipated</span> <span class="NormalTextRun SCXW198344204 BCX8">salary</span> <span class="NormalTextRun SCXW198344204 BCX8">range</span> <span class="NormalTextRun SCXW198344204 BCX8">for</span><span class="NormalTextRun SCXW198344204 BCX8"> this position </span><span class="NormalTextRun SCXW198344204 BCX8">is</span> </span><span class="TextRun SCXW198344204 BCX8" lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW198344204 BCX8">$190,000 to $255,000</span></span><span class="TextRun SCXW198344204 BCX8" lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW198344204 BCX8">.</span> <span class="NormalTextRun SCXW198344204 BCX8">The</span> <span class="NormalTextRun SCXW198344204 BCX8">final</span> <span class="NormalTextRun SCXW198344204 BCX8">salary</span> <span class="NormalTextRun SCXW198344204 BCX8">offered</span> <span class="NormalTextRun SCXW198344204 BCX8">to</span> <span class="NormalTextRun SCXW198344204 BCX8">a</span> <span class="NormalTextRun SCXW198344204 BCX8">successful</span> <span class="NormalTextRun SCXW198344204 BCX8">candidate</span> <span class="NormalTextRun SCXW198344204 BCX8">will</span> <span class="NormalTextRun SCXW198344204 BCX8">be</span> <span class="NormalTextRun SCXW198344204 BCX8">dependent</span> <span class="NormalTextRun SCXW198344204 BCX8">on</span> <span class="NormalTextRun SCXW198344204 BCX8">several</span> <span class="NormalTextRun SCXW198344204 BCX8">factors</span> <span class="NormalTextRun SCXW198344204 BCX8">that</span> <span class="NormalTextRun SCXW198344204 BCX8">may</span> <span class="NormalTextRun SCXW198344204 BCX8">include</span> <span class="NormalTextRun SCXW198344204 BCX8">but</span> <span class="NormalTextRun SCXW198344204 BCX8">are</span> <span class="NormalTextRun SCXW198344204 BCX8">not</span> <span class="NormalTextRun SCXW198344204 BCX8">limited</span> <span class="NormalTextRun SCXW198344204 BCX8">to</span> <span class="NormalTextRun SCXW198344204 BCX8">the</span> <span class="NormalTextRun SCXW198344204 BCX8">type</span> <span class="NormalTextRun SCXW198344204 BCX8">and</span> <span class="NormalTextRun SCXW198344204 BCX8">length</span> <span class="NormalTextRun SCXW198344204 BCX8">of</span> <span class="NormalTextRun SCXW198344204 BCX8">experience</span> <span class="NormalTextRun SCXW198344204 BCX8">within</span> <span class="NormalTextRun SCXW198344204 BCX8">the</span> <span class="NormalTextRun SCXW198344204 BCX8">job,</span> <span class="NormalTextRun SCXW198344204 BCX8">type</span> <span class="NormalTextRun SCXW198344204 BCX8">and</span> <span class="NormalTextRun SCXW198344204 BCX8">length</span> <span class="NormalTextRun SCXW198344204 BCX8">of</span> <span class="NormalTextRun SCXW198344204 BCX8">experience</span> <span class="NormalTextRun SCXW198344204 BCX8">within</span> <span class="NormalTextRun SCXW198344204 BCX8">the</span> <span class="NormalTextRun SCXW198344204 BCX8">industry,</span> <span class="NormalTextRun SCXW198344204 BCX8">education,</span> <span class="NormalTextRun SCXW198344204 BCX8">etc</span><span class="NormalTextRun SCXW198344204 BCX8">etera.</span><span class="NormalTextRun SCXW198344204 BCX8"> In addition to base salary, </span><span class="NormalTextRun SCXW198344204 BCX8">the </span><span class="NormalTextRun SCXW198344204 BCX8">h</span><span class="NormalTextRun SCXW198344204 BCX8">ired applicant will be eligible to receive </span><span class="NormalTextRun SCXW198344204 BCX8">an </span><span class="NormalTextRun SCXW198344204 BCX8">annual bonus and an equity grant at hire and annually in the form of </span><span class="NormalTextRun SCXW198344204 BCX8">the</span><span class="NormalTextRun SCXW198344204 BCX8"> option to purchase stock in the future for a specified price.</span></span></span></span></p><div class="content-conclusion"><p><span class="TextRun SCXW233226884 BCX8" lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW233226884 BCX8">Along with our casual, collaborative</span><span class="NormalTextRun SCXW233226884 BCX8">,</span><span class="NormalTextRun SCXW233226884 BCX8"> and fun work and the chance to make your mark in our mission to erase cancer, </span><span class="NormalTextRun SCXW233226884 BCX8">Erasca</span><span class="NormalTextRun SCXW233226884 BCX8"> offers a comprehensive and competitive benefits package that includes:</span> <span class="NormalTextRun SCXW233226884 BCX8">Paid </span><span class="NormalTextRun SCXW233226884 BCX8">Time Off</span><span class="NormalTextRun SCXW233226884 BCX8">, Holiday</span><span class="NormalTextRun SCXW233226884 BCX8">,</span><span class="NormalTextRun SCXW233226884 BCX8"> and Sick </span><span class="NormalTextRun SCXW233226884 BCX8">Leave</span><span class="NormalTextRun SCXW233226884 BCX8">, </span><span class="NormalTextRun SCXW233226884 BCX8">Medical, Dental and Vision Plans</span><span class="NormalTextRun SCXW233226884 BCX8">, </span><span class="NormalTextRun SCXW233226884 BCX8">Short- and Long-Term Disability</span><span class="NormalTextRun SCXW233226884 BCX8">, </span><span class="NormalTextRun SCXW233226884 BCX8">Basic and Voluntary Life/AD&D Coverage</span><span class="NormalTextRun SCXW233226884 BCX8">, </span><span class="NormalTextRun SCXW233226884 BCX8">Flexible Spending Account</span><span class="NormalTextRun SCXW233226884 BCX8">s</span><span class="NormalTextRun SCXW233226884 BCX8"> (FSA</span><span class="NormalTextRun SCXW233226884 BCX8">,</span> <span class="NormalTextRun SCXW233226884 BCX8">HSA, and Commute</span><span class="NormalTextRun SCXW233226884 BCX8">)</span><span class="NormalTextRun SCXW233226884 BCX8">, Critical Illness and Accident Coverage</span><span class="NormalTextRun SCXW233226884 BCX8">, </span><span class="NormalTextRun SCXW233226884 BCX8">Pet Insurance, </span><span class="NormalTextRun SCXW233226884 BCX8">Employee Assistance Program</span><span class="NormalTextRun SCXW233226884 BCX8">, </span><span class="NormalTextRun SCXW233226884 BCX8">401(k) Plan with </span><span class="NormalTextRun SCXW233226884 BCX8">Erasca</span><span class="NormalTextRun SCXW233226884 BCX8"> contribution</span><span class="NormalTextRun SCXW233226884 BCX8">, and the opportunity to participate in an </span><span class="NormalTextRun SCXW233226884 BCX8">E</span><span class="NormalTextRun SCXW233226884 BCX8">mployee </span><span class="NormalTextRun SCXW233226884 BCX8">S</span><span class="NormalTextRun SCXW233226884 BCX8">tock </span><span class="NormalTextRun SCXW233226884 BCX8">P</span><span class="NormalTextRun SCXW233226884 BCX8">urchase </span><span class="NormalTextRun SCXW233226884 BCX8">P</span><span class="NormalTextRun SCXW233226884 BCX8">rogram.</span></span><span class="EOP SCXW233226884 BCX8" data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}"> </span></p>
<p>Erasca, Inc., is an Equal Opportunity Employer and takes pride in maintaining a diverse and inclusive environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of sex , race, religion, national origin, ancestry, physical or mental disability, protected medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military and veteran status or any other basis protected by federal, state or local law or ordinance or regulation.</p></div>

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