Sr. QA Engineer

Chicago/National: $100,000-$135,000
SF/NY: $115,00-$150,000



Tempus AI is a cutting-edge clinical laboratory coupled with powerful automation capabilities. We continually strive to deliver quality results to our patients as quickly as possible. As a Senior QA Engineer, you will embed with one or more Agile Scrum teams to validate and continuously improve our in-house developed software. This is a hands-on engineering role: you will design and maintain UI, API, and data-validation test frameworks in Java and Python, wire them into CI/CD so they run unattended against every build. You will gain experience with modern test tooling, cloud-native delivery, and AI-assisted testing. Knowledge of genetic testing, molecular biology, or other scientific disciplines is a strong plus but is not required. This is a fantastic opportunity to engage in a positive and creative work environment that offers great benefits and opportunities for growth.

Key Responsibilities

• Participate with your teams in Agile Scrum ceremonies, including backlog grooming, sprint planning, and retrospectives; represent quality and testability from the start of a story, not at the end of the sprint.
• Build and maintain automated tests for web UI, REST APIs and databases, and hold test code to the same standards as production code.
• Own the regression suites for your applications: grow coverage, fix or remove flaky tests, and keep them running in CI/CD after every deployment and nightly.
• Test for HIPAA and SOX compliance, including how PHI is handled, who can access it and what gets logged, and keep tests traceable to requirements.
• Analyze test results and triage failures quickly: separate real product defects from environment, data, and test-harness issues, identify root cause, and drive resolution with clear, reproducible bug reports.
• Validate scheduled night-time and off-hours deployments, and confirm post-deployment health in lower and production environments.
• Participate in risk assessments, validation processes, and release readiness reviews; provide a clear, evidence-based go/no-go quality recommendation.
• Maintain traceability from requirements and specifications through test cases to results, especially for regulated components.
• Apply AI-assisted tooling responsibly to accelerate test authoring, failure triage, and coverage analysis, while remaining accountable for the correctness of every test that ships.
• Mentor junior QA engineers through pairing and code review, and help internal users troubleshoot when needed.

Qualifications

• 8+ years in software QA, including 5+ years writing test automation.
• Strong programming ability in at least one language used for automation, Java and/or Python preferred
• Hands-on UI automation with Playwright or Selenium.
• API testing with REST Assured, Postman or similar, including schema, contract and authentication checks.
• Experience running tests in CI/CD (GitHub Actions, Jenkins, GitLab CI or similar), with reporting such as Allure.
• Solid SQL (e.g., MySQL) and a careful approach to test data when it's regulated.
• Experience with performance and load testing using tools such as JMeter, k6, or Gatling.
• Working knowledge of HIPAA, HL7 and FHIR.
• Bachelor's degree in Computer Science or a related field, or equivalent experience.

Preferred

• ISTQB/ASTQB certification.
• Experience with AWS (ECS/Fargate, Lambda, S3) or Azure, and with Docker.
• Experience in a regulated environment such as a CLIA/CAP lab, FDA, SOX.