Senior Director, Scientific Project Lead (Oncology)

<p><strong>The Role:</strong></p>
<p><span data-contrast="auto"><span data-ccp-parastyle="Body Text">Generate is seeking a </span><span data-ccp-parastyle="Body Text">Senior Director, </span><span data-ccp-parastyle="Body Text">Scientific </span><span data-ccp-parastyle="Body Text">Project Lead, Oncology to lead complex, cross-functional </span><span data-ccp-parastyle="Body Text">scientific </span><span data-ccp-parastyle="Body Text">programs from concept and early discovery through preclinical development, contribute to translational and early development strategy, and manage and develop scientific talent.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></p>
<p><span data-contrast="auto"><span data-ccp-parastyle="Body Text">This role combines formal people management with broad cross-functional leadership across research, platform, translational, preclinical, development, and portfolio functions. Working closely with functional</span><span data-ccp-parastyle="Body Text">, business and technical</span><span data-ccp-parastyle="Body Text"> leaders, </span><span data-ccp-parastyle="Body Text">project managers</span><span data-ccp-parastyle="Body Text">,</span><span data-ccp-parastyle="Body Text"> and senior and executive stakeholders, the </span><span data-ccp-parastyle="Body Text">Scientific </span><span data-ccp-parastyle="Body Text">Project Lead</span><span data-ccp-parastyle="Body Text"> </span><span data-ccp-parastyle="Body Text">will bring deep scientific judgment in therapeutic discovery, strategic program leadership, and operational rigor to align multidisciplinary teams, guide key decisions, represent programs in governance forums, and contribute to portfolio prioritization.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></p>
<p><strong>Here's how you will contribute:</strong></p>
<ul>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Lead complex, cross-functional programs from concept and early discovery through preclinical development, with accountability for scientific strategy, execution quality, team effectiveness, risk management, and stage-gate readiness.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Develop and</span><span data-ccp-parastyle="Body Text">maintain</span><span data-ccp-parastyle="Body Text">integrated program strategies and plans that align scientific </span><span data-ccp-parastyle="Body Text">objectives</span><span data-ccp-parastyle="Body Text">, timelines, dependencies, critical path activities, and resourcing.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Set</span><span data-ccp-parastyle="Body Text">scientific</span><span data-ccp-parastyle="Body Text">program direction and </span><span data-ccp-parastyle="Body Text">identify</span><span data-ccp-parastyle="Body Text"> and advance therapeutic opportunities and target proposals by integrating disease biology, Generate’s differentiated platform capabilities, internal and external evidence, translational and clinical rationale, and competitive intelligence.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text">Facilitate</span><span data-ccp-parastyle="Body Text">cross-functional discussions, resolve divergent perspectives, make clear recommendations, own key </span><span data-ccp-parastyle="Body Text">scientific</span><span data-ccp-parastyle="Body Text"> decisions within the </span><span data-ccp-parastyle="Body Text">project</span><span data-ccp-parastyle="Body Text"> team structure, and drive </span><span data-ccp-parastyle="Body Text">timely</span><span data-ccp-parastyle="Body Text"> go/no-go recommendations.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Drive execution across wet lab, computational, platform, translational, and preclinical workstreams, ensuring scientific rigor, reproducibility, strong documentation, and high-quality data packages.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Develop resource plans and budget assumptions,</span><span data-ccp-parastyle="Body Text">anticipate</span><span data-ccp-parastyle="Body Text">strategic inflection points, and proactively resolve risks, gaps, and cross-functional dependencies.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Build effective operating mechanisms for program planning, governance preparation, risk tracking, decision-making, and cross-functional accountability.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Manage, coach, and develop direct reports through clear</span><span data-ccp-parastyle="Body Text">objectives</span><span data-ccp-parastyle="Body Text">, regular feedback, performance management, compensation recommendations, and career development; mentor cross-functional team members in partnership with their functional managers.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Set clear expectations and foster a high-performing team culture grounded in scientific rigor, accountability, transparency, urgency, collaboration, and constructive challenge.</span></span></li>
</ul>
<p><strong>The Ideal Candidate will have:</strong></p>
<ul>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> PhD, MD, or MD/PhD in cancer biology,</span><span data-ccp-parastyle="Body Text">immun</span><span data-ccp-parastyle="Body Text">o</span><span data-ccp-parastyle="Body Text">-oncology</span><span data-ccp-parastyle="Body Text">, or another discipline relevant to therapeutic discovery and development.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text">12+ years of r</span><span data-ccp-parastyle="Body Text">elevant</span><span data-ccp-parastyle="Body Text">experience in biotech, pharma, academia, or a related scientific environment.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Experience</span><span data-ccp-parastyle="Body Text">identifying</span><span data-ccp-parastyle="Body Text">, evaluating, or advancing therapeutic targets and preclinical programs in oncology.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Experience designing or interpreting preclinical oncology studies, including in vitro functional assays, in vivo efficacy models, and pharmacodynamic or mechanistic studies that connect</span><span data-ccp-parastyle="Body Text">mechanism</span><span data-ccp-parastyle="Body Text">to clinically meaningful hypotheses.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Experience managing and developing scientists or other technical professionals, combined with a strong record of leading multidisciplinary teams through influence.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Experience shaping program strategy, influencing senior stakeholders, and synthesizing complex scientific issues into sound decisions and clear governance recommendations, sometimes with incomplete information, while navigating scientific and resource tradeoffs in a matrixed environment.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Strong operational leadership, learning agility, intellectual curiosity, and comfort</span><span data-ccp-parastyle="Body Text">operating</span><span data-ccp-parastyle="Body Text">in ambiguous and evolving environments, with a practical approach to solving problems and unblocking teams.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></li>
</ul>
<p><strong>Preferred Qualifications:</strong></p>
<ul>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Experience with protein therapeutics and related modalities, including</span><span data-ccp-parastyle="Body Text">multispecific</span><span data-ccp-parastyle="Body Text">antibodies, immune </span><span data-ccp-parastyle="Body Text">engagers</span><span data-ccp-parastyle="Body Text">, antibody-drug conjugates, peptides, or other conjugate-based approaches.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Familiarity with computational protein design, machine learning-enabled discovery, or platform-scale biological systems.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Familiarity with IND-enabling studies and early clinical development for oncology therapeutics.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Experience working effectively with consultants, CROs, and other external partners.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> Comfort using LLM-enabled tools and emerging agentic workflows to support scientific planning, analysis, and execution.</span></span></li>
</ul>
<p><strong>Who Will Love This Job: </strong></p>
<ul>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> A biomedical scientist who enjoys</span><span data-ccp-parastyle="Body Text">identifying</span><span data-ccp-parastyle="Body Text">novel oncology targets and turning early ideas into well-defined therapeutic opportunities.</span></span><span data-ccp-props="{"335559738":180,"335559739":180}"> </span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> A scientifically grounded leader energized by complex programs, consequential decisions, incomplete information, and the opportunity to adapt quickly as new data</span><span data-ccp-parastyle="Body Text">emerge</span><span data-ccp-parastyle="Body Text">.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> An entrepreneurial, hands-on problem solver with an agile mindset who thrives at the interface of cancer biology, platform technologies, translational science, and portfolio strategy.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> A matrix leader who enjoys working and learning across domains, builds trust, sets a high bar, and aligns strong cross-functional partners through influence.</span></span></li>
<li><span data-contrast="auto"><span data-ccp-parastyle="Body Text"> A people leader who enjoys developing talent while building resilient, collaborative, and high-performing teams.</span></span></li>
</ul>
<p><strong>About Generate:Biomedicines</strong></p>
<p class="markdown prose dark:prose-invert w-full wrap-break-word light markdown-new-styling">We are a clinical-stage generative biology company pioneering the AI revolution in drug design and development. We are advancing a new approach to drug creation—one grounded in the ability to design proteins with defined biological intent. By integrating machine learning with large-scale experimentation, this approach aims to reduce the uncertainty, time, and cost associated with developing protein-based medicines.</p>
<p class="markdown prose dark:prose-invert w-full wrap-break-word light markdown-new-styling">Founded in 2018, we are advancing a growing pipeline of clinical and preclinical programs across multiple disease areas and protein modalities. By unifying computational design and clinical development within a single operating model, we translate this approach into clinical-stage programs and are leading a shift from traditional drug discovery toward systematic drug generation.</p>
<p class="markdown prose dark:prose-invert w-full wrap-break-word light markdown-new-styling">At Generate:Biomedicines, we collaborate across disciplines in new ways to invent and innovate. We bring diverse perspectives to a shared goal of delivering better medicines to patients in need, faster, guided by our values and leadership behaviors.</p>
<p>Generate:Biomedicines is <strong>committed to equal employment opportunity</strong> regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.</p>
<p><strong><em>Recruitment & Staffing Agencies</em></strong><em>: Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto.</em></p>
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<p>#LI-RT1</p><div class="content-pay-transparency"><div class="pay-input"><div class="description"><p><strong>Compensation:</strong> The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package.</p></div><div class="title">Per Year Salary Range</div><div class="pay-range"><span>$210,000</span><span class="divider">—</span><span>$300,000 USD</span></div></div></div>