Principal Scientist, Cell Culture

Essential Functions of the job: Be responsible for designing, planning, and executing experiments in upstream process development Develop and manage project plans and timelines. Be accountable for the timely preparation of progress reports and presentations according to agreed plans, milestones, and company guidelines for areas under direct responsibility Design, coordinate and conduct experiments toward cell culture process development, including media screening, feeding strategies optimization and cell culture in plates, deep wells, shake flasks and bioreactors Independently operate laboratory scale bioreactors and other cell culture vessels Troubleshoot and maintain laboratory equipment and instrument associated with the upstream process Author the process development, qualification or validation reports and lead the process transfer to production facility Closely collaborate with other cross-functional teams to provide support in cell line development, downstream process development, formulation development and animal studies Enhance upstream process capabilities by introducing new equipment, process, or technology Effectively and independently solve problems that arise within job responsibilities by evaluating data and information from multiple sources to determine root causes and generate innovative solutions to problems Work independently and collaboratively with internal stakeholders (R&D, technical, manufacturing, regulatory, commercial, legal etc.) to develop strategies, oversee project execution, leverage the collective experience, and share best practices Perform self-directed literature searches and read scientific literatures. Prepare manuscripts for publication and presentations for scientific or marketing meetings. Seek and stay abreast of external advances and technologies that can enhance the process and product development Function as the subject expert in the responsible area and provide support, coaching, or assistance to other team members Required Experience and Skills: o PhD with 2+ years or Masters in life science (Biology, Pharmaceutical Sciences, Bioprocessing, Chemical Engineering or Biomedical engineering) with 6+ years in the biopharmaceutical industry o Hands-on experience in process development and manufacturing of monoclonal antibodies. o Knowledge of quality attributes of glyco-proteins a must. o Hands-on experience in process validation is a plus o Quality mindset and good understanding of Good Manufacturing Practices (GMP) o Excellent presentation and communication skills o Results-oriented with ability to work and deliver under pressure o Excellent English (written, oral) 百济神州全球胜任力 当我们通过以下十二项全球胜任力，展现出 "患者为先"、"无界协作"、"锐意创新 "和 "追求卓越 "的价值观时，我们就能帮助全世界更多患者获得更多负担得起的药品。 ●团队协作 ●提供并征求坦诚及可行的反馈 ●自我认知 ●兼容并蓄 ●积极主动 ●开拓精神 ●持续学习 ●拥抱变化 ●结果导向 ●分析性思维/数据分析 ●卓越财务 ●清晰沟通 BeOne Global Competencies When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. ●Fosters Teamwork ●Provides and Solicits Honest and Actionable Feedback ●Self-Awareness ●Acts Inclusively ●Demonstrates Initiative ●Entrepreneurial Mindset ●Continuous Learning ●Embraces Change ●Results-Oriented ●Analytical Thinking/Data Analysis ●Financial Excellence ●Communicates with Clarity 求职者隐私申明： 百济神州致力于尊重和保护您的个人信息权利，并承诺依据合法、正当、必要和诚信的原则处理您的个人信息（包括个人敏感信息 ）。 由于百济神州在全球范围内开展业务，我们可能需要基于人力资源管理等合理业务目的而将您的个人信息发送和/或存储在位于您所在国家以外其他国家（例如：美国）的服务器和数据库中，详情参见百济神州《求职者隐私政策》（百济神州官网 - 隐私政策 - 求职者隐私政策）。 如您主动向我们提供您的简历信息或其他个人信息，则视为您已经充分理解并确认接受百济神州《求职者隐私政策》内容。如您对此有任何疑问的，请勿提交简历信息或其他个人信息。 BeOne is committed to respect and protect your personal information rights, and will process your personal information, including your sensitive personal information, based on the principles of legality, legitimacy, necessity, and integrity. Due to the reasonable business need for human resource management as a result of BeOne’s global operation, your personal information may be transferred and/ or stored in a server/database located in a third country (e.g., the United States) other than your own country. For further details, please refer to BeOne Job Applicant Privacy Policy (BeOne official website - Privacy Policy - Job Applicant Privacy Policy). If you voluntarily provide your resume or other personal information to us, it is deemed as you have thoroughly acknowledged and accepted BeOne Job Applicant Privacy Policy. If you have any concern, please DO NOT submit your resume or any other personal information.