Research Scientist I

• The Moritz lab at the Institute for Systems Biology (ISB) in Seattle, WA is seeking a Research
• Scientist to join our interdisciplinary team under the direction of Dr. Ulrike Kusebauch to
• advance translational proteomics research in infectious disease systems biology. Our focus will
• be 1) to develop new proteomics approaches to detect post-translational modifications and to
• advance proteomics workflows to accelerate discovery, and 2) to apply these approaches in
• areas of human cancer and infectious disease. Working within a highly collaborative,
• multidisciplinary environment, we have access to the largest collections of comprehensive
• proteomics data sets incorporated into an extensive set of Atlas’s to support the knowledge of
• proteins and their modifications. Our team collaborates with systems biologists, data scientists,
• and domain experts in human and infectious disease at ISB and across the country. The
• applicant will be highly experienced in post-translational modification analysis by mass
• spectrometry, protein expression and purification, and comprehensive data analysis of
• multiplexed datasets. This position offers opportunities for growth and career advancement.

Responsibilities include

• -Design, execute, and evaluate scientific experiments appropriate to project objectives
• -Operate advanced mass-spectrometry instrumentation
• -Process, analyze and interpret proteomics data
• -Prepare research findings for scientific publications
• -Contribute to new research proposals
• -Contribute scientific expertise to various projects
• -Participate in the intellectual life of ISB by attending and presenting at seminars and talks
• -Other duties as assigned

Qualifications

-A Ph.D. in Biochemistry, Biology, Molecular Biotechnology, or related scientific discipline

• Track record of peer-reviewed scientific publications

• -Extensive experience in mass spectrometry-based proteomics
• -Strong expertise in phospho-proteomic workflows, including phospho-peptide enrichment
• and data analysis
• -Expertise operating mass-spectrometry instrumentation
• -Experience with mammalian and/or bacterial cell culture
• -Experience in protein expression and purification
• -Demonstrated ability to work effectively in interdisciplinary teams, adapt to evolving
• priorities, and manage multiple concurrent projects
• -Excellent written communication and documentation skills

Preferred qualifications

• -Experience with plasmid cloning and molecular biology techniques
• -Experience developing Python and R scripts for data analysis and workflow development
• Salary: Expected annual salary between $90-95k DOE
• Benefits: https://isbscience.org/careers/benefit-summary/
• ISB is an EOE D/V.