Scientist II, Downstream Viral Vector Process Development

Responsibilities

• Design, optimize, and scale-up downstream processes for the purification of viral

vectors, with a focus on in vivo gene therapy products and lentiviral vectors.

• Execute experimental plans, analyze data, and provide insightful

recommendations to improve process efficiency, yield, and product quality.

• Collaborate with cross-functional teams, including Upstream Process

• Development, Analytical Development, and Manufacturing, to ensure seamless
• integration of processes.

• Troubleshoot and resolve technical challenges in downstream processes, ensuring

robust and scalable solutions.

• Present internally and to client with project status updates
• Stay abreast of industry trends, emerging technologies, and regulatory guidelines

to contribute to the continuous improvement of processes and compliance.

• Provide direction and leadership to development associates as the team expands.

Qualifications

• Ph.D. or Master’s degree in Chemical Engineering, Biochemical Engineering,

• Biotechnology, or related field with a minimum of 3 years (Ph.D.) or 5 years
• (Master’s) of relevant industry experience

• Proven expertise in downstream process development for viral vectors, with a

focus on AAV and lentiviral vectors.

• Hands-on experience with chromatography, filtration, TFF and other downstream

processing techniques.

• Strong analytical and problem-solving skills, with the ability to interpret complex

data sets.

• Excellent communication skills and the ability to work collaboratively in a team

environment.

• Knowledge of regulatory requirements and quality standards related to

biopharmaceutical manufacturing.

• Experience with formulation science preferred