Postdoctoral Fellow: Medicinal Chemistry & Drug Discovery

What if a single sugar-modifying enzyme held the key to new therapies for cancer, diabetes, and obesity? The Fehl Lab just landed two new NIH grants built around exactly that question, one for chemical tool development and one for treating metabolic disease, and both converge on the same high-value target: O-GlcNAc transferase (OGT). We are hiring a postdoctoral fellow to help take our rationally designed hit compound from bench to preclinical study. This is a rare chance to lead medicinal chemistry on a validated, high-impact target from hit to lead, with a real path toward translational and even commercial impact via Wayne State’s TechTown startup environment. We are chemical biologists who build tools to answer big questions in sugar biology, and we care as much about your growth as we do about the science. You will join a supportive, creative, and diverse group culture at Wayne State University, in the heart of Detroit, with direct mentorship from PI Charlie Fehl and a clear runway toward publications, patents, and your next career step. Our trainees have gone straight to industry, to exciting postdocs at other universities and at the NIH, and even a tenure-track faculty position. Our track record of training and publishing is excellent, and we’re looking for excellent people to join us! Fehl Lab | Department of Chemistry | Wayne State University | Detroit, MI | <fehl-lab.com>