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Track V Bio-Intelligent Manufacturing: Subtrack 1. Protein Components(J28024)

BGI Genomics · 全国

External listingfull-time5 months ago

About The Role

Foundation Models

<1.By> extracting protein “sequence–structure–energy” information, develop large-scale predictive models for extreme protein properties (e.g., thermostability, pH tolerance, salt tolerance), enabling precise prediction, optimization, and rational design of protein performance to support industrial protein applications.

<2.By> integrating sequence, structural, and functional information, construct large-scale models for enzyme function prediction and design. These models will enable efficient mining or rational engineering of probiotic functional elements and cosmetic bioactive biosynthetic components, as well as prediction and optimization of high-efficiency biosynthetic or regulatory pathways, thereby accelerating the development and application of high-performance microbial strains.

Vertical Applications

  • 1.Optimization and rational design of industrial protein performance
  • <2.Engineering> of microbial strains for health interventions and cosmetic ingredient production

Affiliated Branches

  • Changzhou Branch (Changzhou)
  • Hangzhou Branch (Hangzhou)
  • Qingdao Branch (Qingdao)

(1) Preferred Background

Protein Engineering, Structural Biology, Bioinformatics, AI, or Computational Chemistry, Molecular biology or Biocatalysis.

(2) Core Technical Skills

AI-based protein design and optimization, Sequence-Structure-Function Analysis, “Design-construction-testing-optimization” experimental skills.

(3) Modeling Competency

Experience integrating sequence, structure, function, and energy features; enzyme function and robustness optimization.

(4) Preferred Qualifications

Multidisciplinary background in chemical synthesis and biocatalysis, Multidisciplinary background in AI and protein engineering, Industrial enzyme engineering or probiotic strain development experience.

(5) Personal Traits

Strong experimental intuition and interest in industrial biotechnology applications.

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